Why the study?
Does isometric handgrip exercise unmask left ventricular diastolic filling abnormalities in noninsulin-dependent diabetic patients with normal resting filling patterns?
Population
33 noninsulin-dependent diabetic patients with a normal ejection fraction and 15 control subjects.
Comparison
Isometric handgrip exercise evaluated by pulsed… vs Control subjects without diabetes, and resting…
Design
Cross-sectional
Authors
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Exercise Doppler may unmask latent diastolic dysfunction in diabetics with normal rest; hypothesis-generating, needs prospective validation before practice change.
Does isometric handgrip exercise unmask left ventricular diastolic filling abnormalities in noninsulin-dependent diabetic patients with normal resting filling patterns?
Isometric handgrip exercise during Doppler echocardiography can unmask underlying left ventricular diastolic dysfunction in diabetic patients who have normal resting filling patterns.
Tarumi et al. (2008) studied this question.
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