June 13, 2013ACS Catalysis193 citations

Cu/Nitroxyl-Catalyzed Aerobic Oxidation of Primary Amines into Nitriles at Room Temperature

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Abstract

-oxyl). The reactions exhibit excellent functional group compatibility and substrate scope, and are effective with benzylic, allylic and aliphatic amines. Preliminary mechanistic studies suggest that aerobic oxidation of the Cu catalyst is the turnover-limiting step of the reaction.

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Kim et al. (Thu,) studied this question.

synapsesocial.com/papers/6a083315ab15ea61dee8b7c6 https://doi.org/https://doi.org/10.1021/cs400360e

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