The (Z)-allene-ene-yne 10, a precursor to a reactive alpha,3-dehydrotoluene biradical, was covalently linked to a minor groove binding element, and the resultant conjugate (9) was shown to bind and cleave DNA with sequence selectivity.
No takes yet. Share an insight, caveat, or question.
Myers et al. (1996) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: