Key result
Awake off-pump CABG under high thoracic epidural anesthesia succeeds without complications in ~68% of patients.
Why the study?
General anesthesia can be an obstacle for some patients with comorbidities who require mandatory cardiac surgery.
Is awake off-pump coronary artery bypass grafting using high thoracic epidural anesthesia safe and feasible in patients with comorbidities who cannot tolerate general anesthesia?
Observational (n=31)
No
Is awake off-pump coronary artery bypass grafting using high thoracic epidural anesthesia safe and feasible in patients with comorbidities who cannot tolerate general anesthesia?
Awake off-pump CABG using high thoracic epidural anesthesia is a feasible alternative for patients with comorbidities who cannot tolerate general anesthesia, with a 68% success rate without complications.
May support consideration in select patients intolerant to general anesthesia; leaves open need for randomized trials.
Background General anesthesia (GA) can be itself an obstacle to some patients with comorbidities to operate upon a mandatory cardiac surgery.Patients and methods Between January 2013 and May 2017 in the Cardiothoracic Surgery Department, Cairo University Hospitals; 31 patients of awake ‘off-pump’ (without cardiopulmonary bypass) coronary bypass surgery were performed by sternotomy, facilitated by thoracic epidural anesthesia. Analgesia was provided with thoracic epidural anesthesia at T2–3 interspace, using bupivacaine 0.5%, lidocaine 2%, and fentanyl 2 μg/ml until T1–8 dermatomal block was achieved, and then was maintained at 8–12 ml/h throughout the surgery. Success of awake off-pump coronary artery bypass grafting, without GA with appropriate surgical and medical conditions, was the target of the study.Results Thirty-one patients (range, 50–70 years) median, 61 years, weight (range, 70–109 kg) median, 78 kg, underwent surgery. Five (16%) patients needed conversion to GA: the left internal mammary artery was dissected, a saphenous vein graft was needed instead. Awake surgery was successful without complications in 68% of cases.Conclusions Off-pump coronary artery bypass grafting in awake old patients can be considered a safe and feasible technique with convenient surgical outcome especially in patients who cannot tolerate GA.
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Mahmoud et al. (2019) conducted an observational in Coronary artery disease requiring bypass surgery in patients with comorbidities (n=31). Awake off-pump coronary artery bypass grafting using high thoracic epidural anesthesia was evaluated on Success of awake off-pump coronary artery bypass grafting, without general anesthesia with appropriate surgical and medical conditions. Awake off-pump coronary artery bypass grafting using high thoracic epidural anesthesia was successful without complications in 68% of patients, with 16% requiring conversion to general anesthesia.
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