Catalytic Enantioselective Synthesis of Atropisomeric Indoles with an NC Chiral Axis

A pivotal role: In the presence of (R)-(−)-5,5′-bisdi(3,5-di-tert-butyl-4-methoxyphenyl)phosphino-4,4′-bi-1,3-benzodioxole–PdCl2 (R)-SEGPHOS–PdCl2, 5-endo-hydroaminocyclization of achiral ortho-alkynylanilines proceeds in an enantioselective manner to give optically active, axially chiral indoles (see scheme). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.