Transition‐Metal‐Catalyzed Enantioselective 2+2+2 Cycloadditions for the Synthesis of Axially Chiral Biaryls

Recent advances towards a development of novel transition-metal-catalyzed enantioselective 2+2+2 cycloadditions for the synthesis of axially chiral biaryls are reviewed. A number of efficient enantioselective biaryl syntheses were accomplished by chiral cobalt(I), iridium(I), and rhodium(I) complex catalyzed 2+2+2 cycloadditions. Furthermore, the enantioselective synthesis of axially chiral biaryls possessing non-biaryl axial chirality was also developed by using chiral rhodium(I) complexes as catalysts.