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) against dynamic stretching during the early healing phase. The mechanical properties of hydrogel gradually decrease during the late healing phase, minimizing its restriction on physiological movements. In addition, diaphragm defect repair models on female rabbits demonstrate asymmetric porous surfaces can simultaneously prevent visceral adhesion and promote defect healing. Therefore, our hydrogel opens an attractive avenue for the construction of biomimetically hierarchical materials to address the stringent requirements of dynamic tissue defect repair.
He et al. (Thu,) studied this question.