Association of sleep disturbance and sleep apnea with the size of the thoracic aorta and the main pulmonary artery

mean) (B = - 0.176, P = 0.022). The diameter of DTA was positively associated with age (B = 0.112, P < 0.001), body mass index (BMI) (B = 0.184, P = 0.041), and DBP (B = 0.033, P = 0.024), and was negatively associated with TST (B = - 0.006, P = 0.023). Neither nocturnal hypoxia nor TST were associated with the diameter of MPA or the ratio of MPA to AA (PA/A). The aortic or MPA measurements were not associated with SL, SE, WASO or ESS. In patients with OSA, nocturnal hypoxia and sleep duration were associated with the diameter of AA and DTA, respectively. It is suggested that sleep apnea and sleep disturbance may exert effects on the remodeling and enlargement of thoracic large vessels through distinctive mechanisms.