Key result
Surgical LAA closure achieves a ~63% complete closure rate, with purse-string methods performing best.
Why the study?
Does the surgical method of LAA closure affect the rate of complete closure and post-surgical CVA in patients undergoing cardiac surgery?
Cohort (n=150)
No
Does the surgical method of LAA closure affect the rate of complete closure and post-surgical CVA in patients undergoing cardiac surgery?
Post-surgical stroke after LAA closure is more strongly associated with clots on prosthetic valves than with incomplete LAA closure.
Purse-string technique may optimize surgical LAA closure rates; leaves open CVA impact independent of prosthetic valve thrombi.
We observed the highest success rate of complete LAA closure in purse-string method followed by resection method. Interestingly, our results showed that despite the higher rate of residual LAA clot in cases of partial LAA closure, the occurrence of post-surgical CVA was mostly related to the presence of clots on the surface of metallic mitral prostheses rather than the presence of partial LAA closure.
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Peighambari et al. (2022) conducted a cohort in Patients undergoing surgical left atrial appendage closure (n=150). Surgical left atrial appendage closure vs. Different surgical methods (purse-string, suture, ligation, resection) was evaluated on Complete LAA closure (p=0.030). Surgical left atrial appendage closure achieved an overall 63.3% complete closure rate, with the purse-string method demonstrating the highest success rate (75.5%).
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