Key result
In patients after a first myocardial infarction, 4-year mortality was significantly associated with years of smoking (OR 1.10, P=0.025) and increased frequency of exercise (OR 0.42, P=0.013).
Observational (n=804)
BACKGROUND: Death associated with coronary heart disease (CHD) depends in part on the time since the myocardial infarction (MI) and modification of risk factors. METHODS: This observational, retrospective 4-year follow-up study consisted of 804 patients (628 men). The participants completed a questionnaire reporting diet, demographic factors, personal behavior (smoking, physical activity), anthropometry, prior medical conditions (hypertension, diabetes mellitus), and recent medication. RESULTS: During 48 months of follow-up, 12% of men and 15% of women died. Older age, longer duration of smoking, and frequency of exercise were significantly different between survivors and the deceased (P = .014, P = .014, P = .001, respectively). Multivariate analysis revealed associations with years of smoking (odds ratio, OR: 1.10, P = .025), treatment with nitrates (OR: 4.81, P = .024), and increased frequency of exercise (OR: 0.42, P = .013), adjusting for age and gender. CONCLUSIONS: We should emphasize cessation of smoking and increased physical activity in MI survivors. Antismoking programs should start at an early age.
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Kolovou et al. (2009) conducted an observational in First Myocardial Infarction (n=804). Risk factors (smoking, physical activity, nitrates) was evaluated on Mortality (OR 1.10, p=0.025). In patients after a first myocardial infarction, 4-year mortality was significantly associated with years of smoking (OR 1.10, P=0.025) and increased frequency of exercise (OR 0.42, P=0.013).
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