Nomograms for Calculating the Number of Patients Needed for a Clinical Trial with Survival as an Endpoint

David Schoenfeld; Jane R. Richter

doi:10.2307/2530299

March 1, 1982Biometrics

Nomograms for Calculating the Number of Patients Needed for a Clinical Trial with Survival as an Endpoint

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Key Points

This research aims to develop nomograms to determine the sample size for clinical trials focused on survival outcomes.
Developed nomograms based on survival data with an exponential distribution.
Adjusted calculations for consistent patient entry into the trial.
Nomograms provide precise sample size estimations for survival analysis.
Valid for studies where patient survival follows an exponential distribution.

Implication

Nomograms calculate sample size for clinical trial survival endpoints, highlighting their utility in research design.

Abstract

This paper presents nomograms for calculating the sample size for a clinical trial with survival as an endpoint. The nomograms are valid when survival is exponential and patients enter the study uniformly.

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Cite This Study

Schoenfeld et al. (1982) studied this question.

synapsesocial.com/papers/6a0889afad370a6b44de2a2c https://doi.org/10.2307/2530299

View at Publisher

Ask AI

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Nomograms for Calculating the Number of Patients Needed for a Clinical Trial with Survival as an Endpoint

Key Points

Implication

Abstract

Discussion

Cite This Study

Nomograms for Calculating the Number of Patients Needed for a Clinical Trial with Survival as an Endpoint

Key Points

Implication

Abstract

Discussion

Cite This Study

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