Key result
Review details pathogenesis, evaluation, and anti-fibrotic treatment of myocardial fibrosis as an AF substrate.
Why the study?
Myocardial fibrosis is a critical substrate for AF, but myocardial biopsy is invasive and the accuracy of serological markers remains controversial.
Design
Review
Authors
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Myocardial fibrosis evaluation in AF warrants consideration; leaves open prospective validation of anti-fibrotic therapies before clinical adoption.
Myocardial fibrosis plays a central role in the pathogenesis of atrial fibrillation, and targeting fibrotic pathways offers potential new therapeutic avenues.
Li et al. (2022) conducted a review in Myocardial Fibrosis and Atrial Fibrillation. This review summarizes the pathogenesis, serological and imaging evaluation, and anti-fibrosis treatment of myocardial fibrosis as a critical substrate for atrial fibrillation.
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