Key result
AF linked to ~14-fold higher odds of high renal venous stasis index vs sinus rhythm.
Why the study?
AF is a common rhythm disorder whose risk factors warrant early identification, prompting this comparison of renal venous stasis index and intra-renal venous flow patterns between patients with AF and sinus rhythm.
Does atrial fibrillation alter intra-renal venous flow patterns and increase renal venous stasis index compared to sinus rhythm?
Observational (n=68)
Does atrial fibrillation alter intra-renal venous flow patterns and increase renal venous stasis index compared to sinus rhythm?
Atrial fibrillation is associated with impaired intra-renal venous flow and increased renal venous stasis index, suggesting a potential mechanism for renal dysfunction in AF patients.
Answers are grounded in this paper and cite their sources.
AF may contribute to renal dysfunction via venous stasis; hypothesis-generating and requires prospective validation before clinical consideration.
BACKGROUND Atrial fibrillation (AF) is one of the most common heart rhythm disorders. Identification and early treatment of AF risk factors can improve mortality and morbidity rates. This study aimed to compare the renal venous stasis index (RVSI) and intra-renal venous flow (IRVF) patterns evaluated by intra-renal Doppler ultrasonography in patients with AF and sinus rhythm (SR). MATERIAL AND METHODS A total of 68 patients, 34 with AF (lasting >12 months AF) and 34 with SR (no previous diagnosis of AF and no AF attack in 24-h Holter monitoring) were included in the study. The RVSI was calculated, and the IRVF patterns were determined using intra-renal Doppler ultrasonography. High RVSI was defined as >0.12 RVSI. In addition, echocardiography and a 6-min walk test were performed. A model including diabetes mellitus, hypertension, creatine, Pro-BNP, left ventricular ejection fraction, presence of AF, and systolic pulmonary artery pressure was created to evaluate the effects of variables on high RVSI. RESULTS The RVSI value was significantly higher in patients with AF than in those with SR (P=0.004). The SR group exhibited a higher prevalence of the continuous flow pattern, which is one of the IRVF patterns (P=0.015). In contrast, the biphasic flow pattern was observed more frequently in patients with AF (P=0.003). The presence of AF was found to predict the high RVSI (P=0.002, OR=14.134, 95% CI 2.083-71.277). CONCLUSIONS The presence of AF may affect the IRVF and cause an increase in RVSI.
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Öztürk et al. (2023) conducted an observational in Atrial fibrillation (n=68). Atrial fibrillation vs. Sinus rhythm was evaluated on High renal venous stasis index (>0.12) (OR 14.134, 95% CI 2.083-71.277, p=0.002). The presence of atrial fibrillation was a significant predictor of high renal venous stasis index compared to sinus rhythm (OR 14.134; 95% CI 2.083-71.277; P=0.002).
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