Key result
Recurrent chest pain masks underlying lung adenocarcinoma after initial treatment for CHD and GERD.
Why the study?
Chest pain has a complex etiology involving multiple systems, and combinations of conditions can obscure the diagnosis and delay treatment.
Case Report (n=1)
This case highlights the importance of comprehensive screening for multiple etiologies of chest pain, as concurrent conditions like coronary heart disease and GERD can mask symptoms of lung cancer.
Recurrent chest pain refractory to cardiac and reflux therapy may signal occult malignancy; this case report leaves open need for prospective validation.
Chest pain is a common symptom with a complex etiology involving multiple organs and systems. Cardiovascular, digestive and respiratory diseases can cause chest pain. A single condition usually reformulates and can cause this symptom, but a combination of conditions can also cause it. This case reports a 69-year-old male suffered from recurrent chest pain. Coronary heart disease, gastroesophageal reflux disease and left lung adenocarcinoma were diagnosed successively for nearly 1 year. The patients focus on one disease, and the medical staff neglects to deal with multiple diseases simultaneously. Ambiguous evidence and patients' unmotivated attitudes towards treatment make early diagnosis of lung cancer difficult. Treatment for coronary heart disease and gastroesophageal reflux disease masks the symptoms of lung cancer to some extent, resulting in a skewed diagnostic focus. This report highlights the need for clinicians to improve communication with patients to enhance treatment adherence and provide comprehensive screening, identification, and treatment of chest pain etiologies to prevent delays in patient treatment. The findings also suggest that awareness of the therapeutic and prognostic impact of interstitial lung disease on lung cancer should be improved, which is essential for the development of clinical treatment protocols.
No takes yet. Share an insight, caveat, or question.
Zhang et al. (2025) conducted a case report in Chest pain mimicking angina (n=1). Recurrent chest pain in a 69-year-old male masked an underlying left lung adenocarcinoma, which was diagnosed after initial treatments for coronary heart disease and gastroesophageal reflux disease.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: