Key result
Native-valve IE care relies on modified Duke criteria, culture-guided antibiotics, and early surgery.
This review outlines the diagnosis of native-valve infective endocarditis using modified Duke criteria and its management with culture-directed antibiotics and early surgery.
Guides current diagnostic and management decisions in native-valve infective endocarditis; leaves open need for prospective validation of surgical timing.
The diagnosis of infectious endocarditis is based on modified Duke criteria, according to findings on physical examination, echocardiography, microbiologic studies, and imaging of target organs. The selection and duration of antibiotic treatment depend on culture results. Early surgery is indicated in some patients.
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Chambers et al. (2020) studied this question. Diagnosis of native-valve infective endocarditis is based on modified Duke criteria, with management depending on culture-guided antibiotic therapy and early surgery in select cases.
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