Population
Kringle domains of Caenorhabditis elegans Ror receptor tyrosine kinase, rat neurotrypsin, plasminogen…
Design
Preclinical
Authors
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No immediate clinical implications; leaves open evolutionary links between kringle and FN2 domains.
Structural analysis suggests that the neurotrypsin kringle domain may represent an evolutionary intermediate between typical kringle domains and fibronectin type II modules.
Ozhogina et al. (2001) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: