Key result
Abrupt elevation of left ventricular pressure produced an immediate rise in right ventricular systolic pressure, demonstrating that right ventricular pumping function is aided by the left ventricle.
Why the study?
Does left ventricular isovolumic pressure influence right ventricular pressure transients in anesthetized dogs?
Population
Anesthetized dogs
Comparison
Abrupt elevation of left ventricular pressure… vs Normal conduction
Design
Preclinical
Authors
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LV-RV interdependence in dogs; leaves open translation to human ventricular function or failure.
Does left ventricular isovolumic pressure influence right ventricular pressure transients in anesthetized dogs?
The rising portion of the right ventricular pressure pulse is directly influenced by the amplitude and timing of left ventricular isovolumic pressure, suggesting right ventricular pumping is aided by the left ventricle.
Oboler et al. (2008) studied this question. Abrupt elevation of left ventricular pressure and endocardial pacing vs. Normal conduction was evaluated on Right ventricular pressure transients. Abrupt elevation of left ventricular pressure produced an immediate rise in right ventricular systolic pressure, demonstrating that right ventricular pumping function is aided by the left ventricle.