Population
Rat atria (in vitro preparation of combined right and left atria)
Comparison
Atrial distension vs Unstretched atria (zero pressure)
Design
Preclinical
Authors
Loading...
Atrial stretch may alter endocardial barrier function; leaves open relevance to human atrial disease or therapies.
Atrial stretch rapidly and reversibly increases the permeability of the atrial endocardium to large molecules, suggesting a stretch-dependent mechanism for macromolecular transport.
Page et al. (1992) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: