Key result
In vitro standardization can overcome the discrepancy between Doppler and catheter gradients for prosthetic heart valves by coupling them using a pressure loss coefficient dependent on valve geometry.
Why the study?
Does Doppler echocardiography accurately reflect catheter pressure gradients in prosthetic heart valves in vitro?
Does Doppler echocardiography accurately reflect catheter pressure gradients in prosthetic heart valves in vitro?
In vitro standardization using a specific formula can help overcome discrepancies between Doppler and catheter pressure gradients in prosthetic heart valves due to pressure recovery.
May enhance prosthetic valve gradient assessment; leaves open in vivo validation of geometry-based standardization.
Evaluation of prosthetic heart valves using Doppler echocardiography remains still controversial although Doppler technique has become standardized for assessing native heart valve function. One of the reasons is the discrepancy between Doppler and catheter gradient due to pressure recovery. This threshold can be overcome by in vitro standardization effects because both gradients are coupled by /spl Delta/p/sub doppler/=8g/K /spl Delta/p/sub catheter/ with K pressure loss coefficient dependent on prosthetic valve geometry and g gravitational acceleration. The authors try to give some clarification in this matter.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
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Verdonck et al. (2002) studied Prosthetic heart valves. Doppler echocardiography vs. Catheter gradient was evaluated on Pressure gradient discrepancy. In vitro standardization can overcome the discrepancy between Doppler and catheter gradients for prosthetic heart valves by coupling them using a pressure loss coefficient dependent on valve geometry.
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