Key result
In vitro testing of the Omnicarbon 21 mm aortic valve demonstrated mean pressure gradients of 11.9 +/- 4.4 mmHg, an effective orifice area of 1.31 +/- 0.08 cm2, and regurgitation volumes below 3 ml.
Why the study?
What are the hydrodynamic and Doppler echocardiographic characteristics of the Omnicarbon 21 mm aortic valve prosthesis in an in vitro model?
What are the hydrodynamic and Doppler echocardiographic characteristics of the Omnicarbon 21 mm aortic valve prosthesis in an in vitro model?
The Omnicarbon 21 mm aortic valve prosthesis demonstrates acceptable in vitro hydrodynamic performance with low regurgitation volumes.
Acceptable in vitro hemodynamics for the Omnicarbon 21 mm valve; leaves open clinical performance and durability in patients.
The aim of this study was to perform combined hydrodynamic and Doppler echocardiographic tests of the Omnicarbon 21 mm cardiac valve in aortic position in our Pulse Duplicator System for simultaneous assessment of valve performance and valve leakage data. During forward flow conditions, measured mean pressure gradients are between 4.5 and 20.2 mmHg (11.9 +/- 4.4 mmHg) for cardiac outputs between 3.6 and 5.3 /min (4.5 +/- 0.4 /min). Doppler-derived mean pressure gradients are between 2.0 and 170 mmHg (9.3 +/- 3.9 mmHg) for the same flow conditions. Effective Orifice area is 1.31 +/- 0.08 cm2 and the performance index is 0.74 +/- 0.04, using the actual geometric orifice area, and 0.38 +/- 0.02, using the tissue annulus diameter, for a cardiac output of 4.5 +/- 0.4 l/min. Regurgitation volumes are below 3 ml. There is a trend to an effect of valve orientation on hemodynamics.
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Dumont et al. (2002) studied Aortic valve prosthesis testing. Omnicarbon 21 mm cardiac valve was evaluated on Mean pressure gradients, effective orifice area, and regurgitation volumes. In vitro testing of the Omnicarbon 21 mm aortic valve demonstrated mean pressure gradients of 11.9 +/- 4.4 mmHg, an effective orifice area of 1.31 +/- 0.08 cm2, and regurgitation volumes below 3 ml.
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