Key result
Higher LV-MV ring size mismatch linked to ~120% higher 1-year MR recurrence after restrictive annuloplasty.
Why the study?
Is left ventricular to mitral valve ring mismatch associated with recurrent mitral regurgitation in patients with ischemic mitral regurgitation after restrictive ring annuloplasty?
Cohort (n=214)
Yes
Is left ventricular to mitral valve ring mismatch associated with recurrent mitral regurgitation in patients with ischemic mitral regurgitation after restrictive ring annuloplasty?
Effect estimate: OR 2.20 (95% CI 1.05-4.62)
p-value: p=0.038
Left ventricular to mitral valve ring size mismatch is a significant predictor of recurrent MR after ring annuloplasty, suggesting that LV size should be considered when selecting ring size or deciding between repair and replacement.
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May support LV-informed ring sizing in ischemic MR repair; hypothesis-generating and should not yet change practice.
Capoulade et al. (2016) conducted a cohort in Ischemic mitral regurgitation (n=214). LV-MV ring mismatch (LVESd/ring size) was evaluated on Moderate or greater mitral regurgitation at 1 year (OR 2.20, 95% CI 1.05-4.62, p=0.038). Higher LV-MV ring size mismatch was significantly associated with an increased risk of 1-year MR recurrence after restrictive ring annuloplasty (OR per 0.5 increase 2.20; 95% CI 1.05-4.62; P=0.038).
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