A complete theory to assess the longitudinal dispersion of a passive solute injected in an annular porous cavity and subjected to a pulsatile flow is provided. The model serves to ameliorate intrathecal therapies in the cerebrospinal fluid within the subarachnoid cavity, and it highlights the key role of the anatomical fine structures and cerebrospinal fluid pulsations.
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Salerno et al. (2020) studied this question.
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