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April 5, 2026BUNSEKI KAGAKUOpen Access

Surface-enhanced Raman Spectroscopy Based on Chemical Enhancement Using Non-Metal Materials

Yasutaka Kitahama Keisuke GODA

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Key Points

This research aims to address the limitations of traditional surface-enhanced Raman spectroscopy (SERS) by developing non-metal substrates based on chemical enhancement.
Development of various non-metal chemical enhancement SERS substrates.
Evaluation of signal uniformity and measurement durability.
Assessment of detection sensitivity improvements compared to traditional metal-based SERS substrates.
Non-metal SERS substrates showed higher signal uniformity and reproducibility.
Improvement in detection sensitivity was successfully achieved.
Demonstrated potential applications of chemically enhanced SERS substrates.

Implication

Demonstrates enhanced detection sensitivity in non-metal SERS substrates, suggesting broader applications.

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Cite This Study

Kitahama et al. (2026) studied this question.

synapsesocial.com/papers/6a095a877880e6d24efe0828 https://doi.org/10.2116/bunsekikagaku.75.203

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Hybrid SERS Platforms for Enhanced Biochemical SensingReview · 2026
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3Controlled Synthesis of Metal-Insulator-Metal Nanoparticles for Enhanced Raman Spectroscopy2025 · 3 citations
4Different Approaches to Enhance Raman Spectroscopy with Metasurface Structures2024 · 1 citations
5Rational Design and Functional Optimization of Surface‐Enhanced Raman Spectroscopy Substrates: From Material Engineering to BioanalysisReview · 2026 · 1 citations

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