What does this research mean for the field?

An elevated Tmax >4 seconds perfusion deficit volume, particularly above 113 mL, independently predicts worse 90-day functional outcomes in patients with M2 middle cerebral artery occlusions undergoing endovascular treatment. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This study aims to determine if the Tmax >4s volume predicts functional outcomes in M2 MCA occlusion patients receiving endovascular treatment.

May 17, 2026American Journal of NeuroradiologyOpen Access

Elevated T max >4 Seconds Volume Predicts Worse Functional Outcome Following Endovascular Treatment in M2 Middle Cerebral Artery Occlusion

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Authors

IKIman Kiani AKAlireza Kooshki HSHamza Salim

Discussion

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Overview

Retrospective study evaluates Tmax >4s volume's ability to predict outcomes in M2 MCA occlusion patients post EVT, suggesting useful prognostic information.

Key Points

This study aims to determine if the Tmax >4s volume predicts functional outcomes in M2 MCA occlusion patients receiving endovascular treatment.
Retrospective analysis of acute ischemic stroke patients with M2 MCA occlusion who underwent EVT.
Utilized univariable and multivariable logistic regression to analyze outcomes based on Tmax >4s volume.
Adjusted for variables including age, admission NIHSS, ASPECTS, IVT, and mTICI.
130 patients were included, median age 75.5 years.
Tmax >4s volume >113 mL had an AUC of 0.81, indicating strong predictive ability for outcomes.
Higher Tmax >4s volume and admission NIHSS correlated with lower favorable outcome odds (OR: 0.24 and OR: 0.88 respectively).

Cite This Study

Kiani et al. (2026) studied this question.

synapsesocial.com/papers/6a095a877880e6d24efe0857 https://doi.org/10.3174/ajnr.a9416

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May 17, 2026American Journal of NeuroradiologyOpen Access

Elevated T max >4 Seconds Volume Predicts Worse Functional Outcome Following Endovascular Treatment in M2 Middle Cerebral Artery Occlusion

View Full Paper

Ask AI

Bookmark

Authors

IKIman Kiani AKAlireza Kooshki HSHamza Salim

Discussion

Member takes

Overview

Retrospective study evaluates Tmax >4s volume's ability to predict outcomes in M2 MCA occlusion patients post EVT, suggesting useful prognostic information.

Key Points

This study aims to determine if the Tmax >4s volume predicts functional outcomes in M2 MCA occlusion patients receiving endovascular treatment.
Retrospective analysis of acute ischemic stroke patients with M2 MCA occlusion who underwent EVT.
Utilized univariable and multivariable logistic regression to analyze outcomes based on Tmax >4s volume.
Adjusted for variables including age, admission NIHSS, ASPECTS, IVT, and mTICI.
130 patients were included, median age 75.5 years.
Tmax >4s volume >113 mL had an AUC of 0.81, indicating strong predictive ability for outcomes.
Higher Tmax >4s volume and admission NIHSS correlated with lower favorable outcome odds (OR: 0.24 and OR: 0.88 respectively).

Cite This Study

Kiani et al. (2026) studied this question.

synapsesocial.com/papers/6a095a877880e6d24efe0857 https://doi.org/10.3174/ajnr.a9416

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