The Gut–Muscle Axis in Sarcopenia: From Parallel Aging to a Self‐Perpetuating Vicious Cycle

Sarcopenia and gut dysbiosis form a bidirectional vicious cycle where microbial changes drive systemic inflammation and muscle loss. Conversely, declining muscle metabolism further disrupts the microbiome. While “bottom-up” microbial interventions show promise in restoring muscle integrity, more research is needed on “top-down” muscle rejuvenation to fully confirm this interaction. Data sharing is not applicable to this article as no new data were created or analyzed in this study.