Metal-free protocol reduces nitro compounds to amines using tetrahydroxydiboron in water, suggesting a sustainable approach.
A metal-free, rapid, and chemoselective protocol for the nitro reduction of aromatic compounds is reported using tetrahydroxydiboron as reducing agent and 4,4'-bipyridine as organocatalyst. This method provides the transformation to aromatic amines with high functional group tolerance in good to excellent yields, under mild conditions (ambient temperature) and water as solvent.
No takes yet. Share an insight, caveat, or question.
Batzaki et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: