What does this research mean for the field?

Pimpinella anisum (anise) supplementation significantly reduces psychological and menopausal symptoms in menopausal women, and machine learning models can accurately classify these treatment responses. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

The study aims to evaluate the effects of Pimpinella anisum on psychological symptoms and to analyze treatment responses using machine learning.

May 17, 2026Current Pharmaceutical Design

Efficacy of Pimpinella anisum L. in Menopausal Women with Psychological Symptoms: A Randomized Controlled Study Integrated with Machine Learning Analysis

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Authors

ABArfa BegumMinistry of AYUSH ASArshiya SultanaMinistry of AYUSH MHMd Belal Bin HeyatWestlake University

Discussion

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Implication

Randomized trial shows anise improves psychological symptoms in menopausal women, suggesting a safe alternative treatment.

Key Points

The study aims to evaluate the effects of Pimpinella anisum on psychological symptoms and to analyze treatment responses using machine learning.
60 menopausal women were randomized to receive 4 g of anise daily or a placebo for 8 weeks.
Primary outcomes were measured using the DASS-21 scale, and secondary outcomes included the MKI and VHI.
Machine learning classifiers, including KNN and Random Forest, were used to analyze treatment response.
Anise significantly reduced DASS-21 scores at 8 weeks (p < 0.0001) with over 80% reporting no symptoms of depression, anxiety, or stress.
Significant improvements in MKI and VHI scores were noted for the anise group (p < 0.0001), unlike the placebo group.
The KNN model achieved a 99.20% accuracy in classifying treatment group membership.

Cite This Study

Begum et al. (2026) studied this question.

synapsesocial.com/papers/6a095b787880e6d24efe1386 https://doi.org/10.2174/0113816128433736260209142133

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Efficacy of Pimpinella anisum L. in Menopausal Women with Psychological Symptoms: A Randomized Controlled Study Integrated with Machine Learning Analysis

Discussion

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Implication

Key Points

Cite This Study

Efficacy of Pimpinella anisum L. in Menopausal Women with Psychological Symptoms: A Randomized Controlled Study Integrated with Machine Learning Analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

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