Pharmacodynamics and mechanisms of triterpene components from the leaves of Astragalus mongholicus Bunge in the treatment of Alzheimer’s disease

Key Points

• The study aims to explore the pharmacodynamics and mechanisms behind triterpenoids from Astragalus mongholicus Bunge for treating Alzheimer's disease.
• Investigated mechanisms of action of triterpenoids from Astragalus mongholicus Bunge
• Evaluated therapeutic effects on Alzheimer's disease models
• Analyzed pharmacodynamic properties and underlying biochemical pathways
• Triterpenoids showed significant improvement in cognitive function as measured by standardized tests
• Demonstrated reduction in amyloid-beta levels (p<0.05)
• Enhanced neuroprotective effects through modulation of neuroinflammation pathways