Key result
Continuous infusion epidural analgesia during labour increased the rate of normal delivery compared to conventional topped-up epidurals (49% vs 30%, P<0.05).
Why the study?
Does continuous infusion epidural analgesia improve the rate of normal delivery compared to conventional 'topped-up' epidurals in patients in labour?
RCT (n=149)
Does continuous infusion epidural analgesia improve the rate of normal delivery compared to conventional 'topped-up' epidurals in patients in labour?
Continuous infusion epidural analgesia during labour increases the likelihood of a normal delivery and reduces the need for obstetric intervention for maternal distress compared to conventional top-ups.
May support infusion epidurals in labour; hypothesis-generating and requires RCTs before practice change.
SummaryA prospective controlled trial was undertaken to investigate the efficacy of continuous infusion epidural analgesia in labour compared to conventional 'topped-up' epidurals. There were 70 patients with continuous infusions and 79 in the 'topped-up' group. Clinical parameters and duration of labour did not differ between the groups. More patients having continuous infusions (49 per cent) delivered normally than in those who were topped-up (30 per cent, P < 005). The incidence of low cavity instrumental delivery was correspondingly higher in the 'topped-up' patients (65 versus 45 per cent). The incidence of obstetric intervention for maternal distress was higher (P < 0-001) in the 'topped-up' patients. There was no difference between the groups with regard to perinatal outcome although the infusion patients had a higher mean cord artery pH level. A reduced workload for the anaesthetist was confirmed with the infusion technique.
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Quinn et al. (1993) conducted an RCT in Labour (n=149). Continuous infusion epidural analgesia vs. Conventional 'topped-up' epidurals was evaluated on Normal delivery (p=<0.05). Continuous infusion epidural analgesia during labour increased the rate of normal delivery compared to conventional topped-up epidurals (49% vs 30%, P<0.05).
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