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Scrub typhus can rarely lead to severe complications such as infection-associated haemophagocytic lymphohistiocytosis (HLH) in pediatric patients. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

May 17, 2026Tropical Doctor0 citations

Infection-associated haemophagocytic lymphohistiocytosis in scrub typhus: A diagnostic enigma – A paediatric case series

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SShambhaviIndian Institute of Technology Dhanbad AMAnand Kumar ManjhiShaheed Suhrawardy Medical College MFMd Rizwan FarooqueeShaheed Suhrawardy Medical College

Key Points

This research examines the occurrence of infection-associated haemophagocytic lymphohistiocytosis (HLH) in children diagnosed with scrub typhus.
Case series analysis of pediatric patients with scrub typhus complications.
Diagnosis of HLH based on clinical and laboratory findings.
Assessment of severity and outcomes associated with HLH.
HLH was identified in a subset of pediatric scrub typhus patients.
Complications of HLH increased the severity of scrub typhus infections.
Early diagnosis and treatment of HLH significantly improved patient outcomes.

Abstract

Scrub typhus, though common, gives rise rarely to severe complications such as infection-associated haemophagocytic lymphohistiocytosis (HLH) in children.

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Cite This Study

Shambhavi et al. (Fri,) studied this question.

synapsesocial.com/papers/6a095c147880e6d24efe21cd https://doi.org/https://doi.org/10.1177/00494755261449086

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