Key result
Multimodality RV and RV-PA coupling imaging optimizes patient selection for transcatheter tricuspid valve interventions.
Why the study?
Right heart dysfunction is frequently observed before and after TTVI and is linked to adverse clinical outcomes, necessitating a comprehensive understanding of right heart anatomy and physiology.
A comprehensive, standardized imaging assessment of right ventricular function and right ventricle-pulmonary artery coupling is critical to guide patient selection and evaluate long-term outcomes in transcatheter tricuspid valve interventions.
With the growing global adoption of transcatheter tricuspid valve intervention (TTVI) and the increasing number of available devices, a comprehensive understanding of right heart dysfunction has become essential. Right heart dysfunction is frequently observed both before and after TTVI and is associated with adverse clinical outcomes. Therefore, a thorough understanding of right heart anatomy and physiology is critical for accurately assessing its pathological states. This review synthesizes current knowledge by integrating findings from major landmark studies on TTVI, with a focus on the available assessment tools for predicting patient outcomes. The anatomy section systematically reviews each component of the right heart-the right atrium, right ventricle, tricuspid valve, and pulmonary valve -while the physiology section emphasizes microstructural characteristics and the pressure-volume relationships. In addition, recommendations from the Tricuspid Valve Academic Research Consortium and the imaging parameters used in recent studies are discussed. Finally, future directions for imaging-based assessment of right heart function in the context of TTVI are highlighted.
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Lee et al. (2025) conducted a review in Severe tricuspid regurgitation and right ventricular dysfunction. Transcatheter tricuspid valve intervention (TTVI) was evaluated. Transcatheter tricuspid valve interventions require a comprehensive, multimodality imaging assessment of right ventricular function and RV-PA coupling to optimize patient selection and clinical outcomes.
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