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under pulsed 800 nm irradiation, confirming activation of the PSs by photoluminescence emitted from NSs. TNBC cells readily internalize NS PS conjugates, which generate reactive oxygen species in the cells upon pulsed NIR irradiation to damage DNA and induce apoptosis. Together, these findings demonstrate that exploiting photoluminescent NSs as carriers of efficient PdDMBil1 PSs is an effective strategy to enable NIR light-activated tandem PDT/PTT.
Wang et al. (Fri,) studied this question.