Baroreflex gain assessed by the modified-Oxford technique was attenuated and accompanied by an increased operating range in middle-aged patients with Parkinson's disease.
Observational
Does the modified-Oxford technique detect cardiovagal-baroreflex dysfunction better than spontaneous indices in middle-aged patients with Parkinson's disease?
Cardiovascular perturbations using the modified-Oxford technique are necessary to detect cardiovagal-baroreflex dysfunction in middle-aged patients with Parkinson's disease, as spontaneous indices are insufficient.
Attenuated baroreflex gain may contribute to adverse cardiovascular outcomes, including orthostatic intolerance symptoms typically observed in patients with Parkinson's disease. We found that the baroreflex gain (assessed by the modified-Oxford technique) is attenuated and accompanied by an increased operating range in patients with Parkinson's disease. These findings highlight that cardiovascular perturbations are required to detect baroreflex impairments and that spontaneous indices do not reveal cardiovagal-baroreflex dysfunction in a middle-aged group of patients with Parkinson's disease.
Sabino‐Carvalho et al. (Wed,) conducted a observational in Parkinson's disease. Modified-Oxford technique vs. Spontaneous indices was evaluated on Baroreflex gain. Baroreflex gain assessed by the modified-Oxford technique was attenuated and accompanied by an increased operating range in middle-aged patients with Parkinson's disease.
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