Key result
IABP placement over visceral arteries reduces mesenteric and celiac flow up to ~24% vs proximal positioning.
Why the study?
Does IABP malposition covering visceral arteries reduce visceral artery perfusion in an acute pig model?
Does IABP malposition covering visceral arteries reduce visceral artery perfusion in an acute pig model?
IABP malposition covering visceral arteries significantly reduces mesenteric and celiac artery perfusion in an acute pig model, highlighting the critical importance of correct device positioning.
IABP malposition may impair visceral perfusion; animal data leave open effects on human positioning and outcomes.
Visceral artery perfusion can be potentially affected by intra-aortic balloon pump (IABP) catheters. We utilized an animal model to quantify the acute impact of a low balloon position on mesenteric artery perfusion. In six pigs (78 ± 7 kg), a 30-cc IABP was placed in the descending aorta in a transfemoral procedure. The celiac artery (CA) and the cranial mesenteric artery (CMA) were surgically dissected. Transit time blood flow was measured for (i) baseline, (ii) 1:1 augmentation with the balloon proximal to the visceral arteries, and (iii) 1:1 augmentation with the balloon covering the visceral arteries. Blood flow in the CMA and CA was reduced by 17 and 24%, respectively, when the balloon compromised visceral arteries compared with a position above the visceral arteries (flow in mL/min: CMA: (i) 1281 ± 512, (ii) 1389 ± 287, (iii) 1064 ± 276, P < 0.05 for 3 vs. 1 and 3 vs. 2; CA: (i) 885 ± 370, (ii) 819 ± 297, (iii) 673 ± 315; P < 0.05 for 3 vs. 1). The covering of visceral arteries by an IABP balloon causes a significant reduction of visceral artery perfusion; thus, the positioning of this device during implantation is critical for obtaining a satisfactory outcome.
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Vondran et al. (2015) studied Visceral artery perfusion (n=6). IABP covering the visceral arteries vs. IABP proximal to the visceral arteries was evaluated on Blood flow in the cranial mesenteric artery (CMA) and celiac artery (CA) (p=<0.05). IABP placement covering the visceral arteries significantly reduced blood flow in the cranial mesenteric artery by 17% and celiac artery by 24% compared to a proximal position (P<0.05).
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