Key result
Dietary polyphenols modulate arterial stiffness mechanisms via gut microbiome metabolism.
Why the study?
Recent studies indicate dietary polyphenols interfere with mechanisms of arterial stiffness progression, motivating a summary of epidemiological and interventional data on polyphenol effects and underlying mechanisms.
Do dietary polyphenols improve arterial stiffness?
Design
Review of epidemiological and interventional studies
Authors
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May position gut microbiome as modulator of polyphenol effects on stiffness; leaves open clinical translation.
Do dietary polyphenols improve arterial stiffness?
Dietary polyphenols and their interaction with the gut microbiome represent a potential therapeutic target for mitigating age-related arterial stiffness.
Bruyne et al. (2019) conducted a review in Arterial stiffness. Dietary polyphenols was evaluated. Dietary polyphenols interact with mechanisms involved in the pathophysiology of arterial stiffness, with effects mediated directly or indirectly by gut microbiome-related metabolism.
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