Key result
C2HEST and HATCH scores predict late AF recurrence after RFA with similar accuracy.
Why the study?
This study aimed to investigate the risk of recurrence in patients with AF after radiofrequency ablation and predict this risk using the C2HEST and HATCH scores.
Does the C2HEST score predict late recurrence of atrial fibrillation after radiofrequency ablation as well as the HATCH score in patients with AF?
Cohort (n=261)
No
Does the C2HEST score predict late recurrence of atrial fibrillation after radiofrequency ablation as well as the HATCH score in patients with AF?
Both C2HEST and HATCH scores are effective and comparable in predicting late recurrence of atrial fibrillation after radiofrequency ablation, with hypertension and heart failure being the strongest contributors.
Answers are grounded in this paper and cite their sources.
C2HEST may offer a comparable alternative to HATCH for post-ablation AF recurrence risk assessment; leaves open need for prospective validation.
Objective This study was aimed to investigate the risk of recurrence in patients with atrial fibrillation (AF) after radiofrequency ablation and predict risk of recurrence using C2HEST and HATCH scores. Methods We retrospectively included 322 patients with AF from Second Hospital of Lanzhou University, and 261 patients were included in the analysis finally. They had AF and were admitted for radiofrequency catheter ablation. We compared the ability of C2HEST and HATCH scores to predict recurrence after radiofrequency ablation of AF. The predictive ability of C2HEST and HATCH scores for AF recurrence was estimated by the area under the receiver operating characteristic curve (AUROC). The difference in receiver operating characteristic curve between the two models was compared using the DeLong test. Results Of the 261 patients included in the analysis, 83 (31.6%) patients suffered a late recurrence of AF after radiofrequency ablation. The risk of postoperative recurrence of AF increased with increasing C2HEST and HATCH scores. The AUROC of C2HEST and HATCH scores in predicting postoperative recurrence of AF was 0.773 (95%CI, 0.713–0.833) and 0.801 (95% CI, 0.740–0.861), respectively. There was no significant difference between the two models in their ability to evaluate patients for postoperative recurrence of AF (DeLong test p -value = 0.36). Among the risk factors in both models, hypertension and heart failure (HF) contributed the most to postoperative recurrence after AF, and higher blood pressure and lower cardiac ejection fraction (EF) were associated with a higher risk of recurrence. Conclusion Both C2HEST and HATCH scores were significantly associated with the risk of late recurrence after radiofrequency ablation of AF. Besides hypertension and HF contributed the most to postoperative recurrence after AF.
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Han et al. (2022) conducted a cohort in Atrial fibrillation (n=261). C2HEST score vs. HATCH score was evaluated on Prediction of late recurrence of atrial fibrillation after radiofrequency ablation (AUROC) (p=0.36). The C2HEST and HATCH scores demonstrated similar and effective predictive ability for late recurrence of atrial fibrillation after radiofrequency ablation, with AUROCs of 0.773 and 0.801, respectively (p=0.36).
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