Key result
QTc dispersion was significantly larger in post-myocardial infarction patients compared to normal subjects across all lead configurations (e.g., in XYZ, 21 ± 13 vs 9 ± 7 ms, P<0.0001).
Why the study?
Does the choice of ECG lead configuration (orthogonal vs 12-lead) affect the measured magnitude of QTc dispersion in normal subjects and post-MI patients?
Observational (n=163)
Does the choice of ECG lead configuration (orthogonal vs 12-lead) affect the measured magnitude of QTc dispersion in normal subjects and post-MI patients?
p-value: p=<0.0001
The magnitude of QT dispersion depends on the ECG lead configuration used, though orthogonal configurations still differentiate post-MI patients from normal subjects.
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ECG lead selection influences QTc dispersion magnitude; leaves open its role in post-MI risk stratification.
Beuve et al. (1999) conducted an observational in Myocardial infarction (n=163). 12-lead, orthogonal (XYZ), and quasi-orthogonal (IF2) ECG configurations vs. Normal subjects vs post-MI patients was evaluated on QTc dispersion (p=<0.0001). QTc dispersion was significantly larger in post-myocardial infarction patients compared to normal subjects across all lead configurations (e.g., in XYZ, 21 ± 13 vs 9 ± 7 ms, P<0.0001).
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