Thymol derivatives from essential oil of Doronicum corsicum L.

The essential oil of Doronicum corsicum L. (Asteraceae), an endemic species from Corsica, has been studied by GC, GC–MS(EI and CI), 1 H‐ and 13 C‐NMR; 129 components were identified, representing 80.4% of the total amount. The essential oil was dominated by sesquiterpene hydrocarbons (38.2%) and oxygenated monoterpenes (36.7%). The major components were modhephene (11.6%), ( E )‐ β ‐caryophyllene (9.8%), 10‐isobutyryloxy‐8,9‐epoxythymyl angelate (9.9%) and thymyl angelate (8.7%). The structures of the two thymol derivatives, the 13 C‐NMR data of four other thymol derivatives and the chemical composition of the essential oil of D. corsicum were reported for the first time.