Why the study?
Does stimulation synchronized with diastolic phases of cerebral pulse pressure waves elicit an evoked vascular response compared to systolic phases?
Does stimulation synchronized with diastolic phases of cerebral pulse pressure waves elicit an evoked vascular response compared to systolic phases?
The evoked vascular response may be a neurally mediated event in anticipation of altered metabolic demand, offering the possibility of real-time measurement.
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Diastolic-timed stimulation may elicit anticipatory neurovascular responses; hypothesis-generating for real-time cerebral monitoring and requires validation.
Sandman et al. (1984) studied this question.
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