Analysis of 178 rotavirus strains from children in Bangui showed that 81.6% belonged to subgroup II, with serotype 1 being the most prevalent (71.3%), followed by serotype 2 (15.4%) and 3 (13.3%).
Observational (n=178)
No
The study identified the predominant rotavirus subgroups and serotypes circulating among children in Bangui, Central African Republic over a 27-month period.
The subgroups and serotypes of 178 strains of rotavirus isolated from diarrheic and healthy children in Bangui, Central African Republic, during a 27-month period were determined by enzyme-linked immunosorbent assay. The subgroup was determined for 152 of the viral strains, 18.4% being subgroup I and 81.6% being subgroup II. Of the 143 strains which could be serotyped, 71.3% were serotype 1, 15.4% were serotype 2, and 13.3% were serotype 3. Serotypes 1 and 3 were detected throughout the study, while serotype 2 was detected only during 8 months. No serotype exhibited any special epidemiological properties. The serotypes were found to consist of three different electrophoretypes, two long ones (A and B) and a short one (C). All subgroup I, serotype 2 strains presented short electrophoretypes. Strains with identical long electrophoretypes A were either serotype 1 or serotype 3.
Georges-Courbot et al. (Fri,) conducted a observational in Rotavirus infection (n=178). Analysis of 178 rotavirus strains from children in Bangui showed that 81.6% belonged to subgroup II, with serotype 1 being the most prevalent (71.3%), followed by serotype 2 (15.4%) and 3 (13.3%).