NMS-associated rhabdomyolysis-induced AKI complicated by sepsis and contrast exposure led to prolonged renal replacement therapy, with dialysis independence achieved only after 2 months.
Case Report (n=1)
NMS-associated rhabdomyolysis-induced AKI can require prolonged hemodialysis, especially when compounded by other renal insults like sepsis and contrast exposure.
Neuroleptic malignant syndrome (NMS) can be complicated by rhabdomyolysis, a known cause of acute kidney injury (AKI) that typically resolves within a short period. However, some cases of NMS-associated rhabdomyolysis require hemodialysis. We report a woman in her fifties who developed AKI secondary to NMS-associated rhabdomyolysis and required prolonged renal replacement therapy (RRT). She experienced sepsis and contrast exposure, and dialysis independence was achieved only after 2 months, the longest reported duration. This case highlights that NMS-associated rhabdomyolysis-induced AKI may lead to prolonged dialysis, particularly in the presence of additional risk factors for renal injury.
中田ら（木曜日）は、急性腎障害を伴った神経性悪性症候群関連の横紋筋融解症に関する症例報告を行いました（n=1）。腎代替療法（血液透析）は、透析独立性について評価されました。NMS関連横紋筋融解症によるAKIは、敗血症および造影剤の影響によって複雑化し、長期の腎代替療法が必要となり、透析独立性は2ヶ月後に達成されました。
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