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May 18, 2026Hearing ResearchOpen Access

How (not) to study deviance sensitivity and predictive coding in auditory cortex

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Authors

INIsrael NelkenDMDina Moshitch

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Overview

The article examines deviance sensitivity in the auditory cortex, highlighting methodological challenges and implications.

Key Points

  • This research aims to clarify the complexities of measuring deviance sensitivity and prediction errors in auditory responses.
  • Analyzed existing paradigms, particularly the auditory oddball sequence, for assessing brain responses to sounds.
  • Critiqued the use of control sequences in interpreting deviance sensitivity, emphasizing the role of mechanistic models.
  • Discussed simulation results from auditory cortical dynamics models to reveal limitations in standard comparison methods.
  • Demonstrated that the presence of 'deviant>control' responses is not a reliable indicator of deviance sensitivity.
  • Showed how adaptation models can create misleading deviant>control effects depending on design choices.
  • Concluded that proper demonstration of deviance sensitivity requires explicit mechanistic modeling.

Cite This Study

Nelken et al. (2026) studied this question.

synapsesocial.com/papers/6a0aac955ba8ef6d83b6fe39https://doi.org/10.1016/j.heares.2026.109672
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