Optimization of 6-Mercaptopurine Therapy in Indians-Specific Adaptation of Global Pharmacogenomics Guideline

Pharmacogenomics is the study about individual’s genetic makeup influences their response to medications, including drug efficacy, toxicity, and the likelihood of beneficial or adverse effects. The primary objective of pharmacogenomics is to optimize drug selection, dosing and combination therapies according to a patient’s genetic profile. Consequently, modern healthcare is progressively transitioning from a traditional “one-size-fits-all” approach toward individualized treatment strategies that emphasize delivering the right drug, at the right dose, at the right time, and in the right manner.