Family care and social alienation in patients with colorectal cancer and an ostomy: The sequential mediating effects of resilience and stigma

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Key Points

This research investigates how family care impacts social alienation in colorectal cancer patients with an ostomy, highlighting resilience and stigma as mediators.
Conducted a cross-sectional study with 290 CRC patients with an ostomy in Fujian Province, China.
Participants completed questionnaires on family care, resilience, stigma, and social alienation.
Utilized serial multiple mediation analysis with a bootstrapping method to test the hypothesized pathways.
Family care negatively correlated with social alienation (r = -0.526, P < 0.001) and stigma (r = -0.483, P < 0.001).
Resilience was positively correlated with family care (r = 0.473, P < 0.001).
Resilience and stigma together mediated 54.26% of the total effect between family care and social alienation.

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Cross-sectional study explores family care's impact on social alienation, resilience, and stigma in CRC patients with ostomies.

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Chen et al. (2026) studied this question.

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