miR-495 Inhibits Proliferation, Migration, and Invasion and Induces Apoptosis via Inhibiting PBX3 in Melanoma Cells [Retraction]

Q: What does this research mean for the field?

The previously published findings regarding the role of miR-495 in inhibiting melanoma cell proliferation, migration, and invasion via PBX3 are invalid due to confirmed image manipulation. Novelty: ClaimNovelty.CONTRADICTORY. Consensus alignment: ConsensusAlignment.NEUTRAL.

Guangxiong Chen; Yijie Xie

doi:10.2147/ott.s624309

May 1, 2026OncoTargets and TherapyOpen Access

miR-495 Inhibits Proliferation, Migration, and Invasion and Induces Apoptosis via Inhibiting PBX3 in Melanoma Cells [Retraction]

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Key Points

The aim was to explore how miR-495 affects melanoma cell behaviors like proliferation and invasion through PBX3 inhibition.
Investigation revealed image panel similarities in Figure 2D.
Differences in treatment conditions were scrutinized by the Journal and Publisher.
Retraction addresses concerns about the validity of claims made regarding miR-495's effects.
No confirmed effects on melanoma cells due to image integrity issues.

Implication

Retraction highlights concerns regarding image integrity in a study examining melanoma cell behaviors.

Abstract

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Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/6a0aad145ba8ef6d83b70941 https://doi.org/10.2147/ott.s624309

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miR-495 Inhibits Proliferation, Migration, and Invasion and Induces Apoptosis via Inhibiting PBX3 in Melanoma Cells [Retraction]

Key Points

Implication

Abstract

Discussion

Cite This Study

miR-495 Inhibits Proliferation, Migration, and Invasion and Induces Apoptosis via Inhibiting PBX3 in Melanoma Cells [Retraction]

Key Points

Implication

Abstract

Discussion

Cite This Study

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