Key result
In children with idiopathic dilated cardiomyopathy, prolonged QRS duration was significantly associated with poor clinical outcomes or death (84 msec vs 66 msec), whereas QT dispersion did not predict prognosis.
Why the study?
Does surface electrocardiogram QRS duration or QT dispersion predict clinical outcomes and ventricular dimensions in children with idiopathic dilated cardiomyopathy?
Observational (n=33)
Yes
Does surface electrocardiogram QRS duration or QT dispersion predict clinical outcomes and ventricular dimensions in children with idiopathic dilated cardiomyopathy?
In children with idiopathic dilated cardiomyopathy, QRS duration correlates with ventricular dimensions and clinical outcomes, whereas QT dispersion does not predict long-term prognosis.
QRS duration may aid risk stratification in pediatric idiopathic dilated cardiomyopathy; leaves open prospective validation before clinical use.
We investigated the interrelations between surface electrocardiographic changes and clinical outcomes in children with idiopathic dilated cardiomyopathy (DCMP). 33 patients (19 boys, 14 girls) were classified into two groups; group I (15) who were in poor clinical status or dead; and group II (18) who showed good clinical status. Group I had larger LV dimensions compared to group II (Gr I vs. Gr II; LVEDD, 52 +/-11 vs. 42+/-7 (mm); LVESD, 43+/-12 vs. 30+/-5 (mm); p<0.05). QRS duration was prolonged in Gr I compared to Gr II and normal (Gr I, 84+/-28; Gr II, 66+/-12; normal control, 67+/-9). The QRS duration was correlated with the dimensions of left ventricle (LV). Corrected QT and JT interval and dispersions of QT in the DCMP group showed a significant difference compared to the normal control, however there was no significant difference between Gr I and II. In conclusion, QRS duration was correlated with ventricular dimension and clinical outcome in children with idiopathic dilated cardiomyopathy. Irrespective of increased ventricular inhomogeneity, QT dispersion could not be used to predict long-term prognosis.
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Huh et al. (2004) conducted an observational in Idiopathic dilated cardiomyopathy (n=33). Surface ECG (QRS duration) vs. Improved clinical status (Group II) was evaluated on QRS duration in patients with poor clinical status or death (Group I) compared to those with improved status (Group II) (p=<0.05). In children with idiopathic dilated cardiomyopathy, prolonged QRS duration was significantly associated with poor clinical outcomes or death (84 msec vs 66 msec), whereas QT dispersion did not predict prognosis.
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