Post-oral administration of Dai-saiko-to extract (TJ-8), a traditional herbal medicine, ameliorated acute liver injury in rats intoxicated with carbon tetrachloride (CCl4). This TJ-8 administration inhibited an increase in lipid peroxide contents in the liver homogenate and microsomal fraction and a decrease in glucose-6-phosphatase activity in the liver microsomal fraction, an index of lipid peroxidation-mediated damage in liver microsomes, during the progression and recovery of the liver injury. These results indicate that the antilipid peroxidative action of TJ-8 contributes to its preventive effect on CCl4-induced acute liver injury in rats.
No takes yet. Share an insight, caveat, or question.
Ohta et al. (1998) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: