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June 1, 1979Annual Review of Biochemistry470 citations

The Structure and Function of Eukaryotic Ribosomes

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IWIra G. Wool

Key Points

  • This research aims to explore the role of the Hippo pathway in regulating growth and development in eukaryotic organisms.
  • Analyzed the role of the Hippo pathway using model organisms like Drosophila melanogaster.
  • Investigated key molecular interactions within the signaling cascade.
  • Assessed the impact of Hippo pathway activation on cell growth and organ size.
  • Activation of the Hippo pathway significantly reduces tissue growth in experimental models.
  • Drosophila studies indicate a direct correlation between Hippo signaling and organ size regulation.
  • Identified key molecular targets indicative of Hippo pathway functionality.

Abstract

The Hippo pathway was initially discovered in Drosophila melanogaster as a key regulator of tissue growth. It is an evolutionarily conserved signaling cascade regulating numerous biological processes, including cell growth and fate decision, organ size ...Read More

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Cite This Study

Ira G. Wool (1979) studied this question.

synapsesocial.com/papers/6a0b9d1de08198424b95d113https://doi.org/10.1146/annurev.bi.48.070179.003443
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