Participation of Lysosomes in Cellular Autophagy Induced in Rat Liver by Glucagon

Russell L. Deter; Pierre Baudhuin; Christian de Duve

doi:10.1083/jcb.35.2.c11

November 1, 1967The Journal of Cell BiologyOpen Access

Participation of Lysosomes in Cellular Autophagy Induced in Rat Liver by Glucagon

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Key Points

To examine the involvement of lysosomes in hepatic cellular autophagy triggered by glucagon administration in rat models.
In vivo evaluation of rat liver tissue response following glucagon administration.
Analysis of hepatic cellular structures to track lysosomal dynamics during the induction of autophagy.
Glucagon induction directly stimulates cellular autophagy within rat liver tissue.
Lysosomes actively engage in the sequestration and degradation processes of cytoplasmic components.

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Implication

Experimental study demonstrates lysosomal involvement in glucagon-induced autophagy in rat liver, highlighting mechanisms of cellular self-degradation.

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Deter et al. (1967) studied this question.

synapsesocial.com/papers/6a0b9d6e71bf22a7f695da5f https://doi.org/10.1083/jcb.35.2.c11

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Participation of Lysosomes in Cellular Autophagy Induced in Rat Liver by Glucagon

Key Points

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Implication

Abstract

Discussion

Cite This Study

Participation of Lysosomes in Cellular Autophagy Induced in Rat Liver by Glucagon

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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