Key result
Perphenazine treatment caused neuroleptic malignant syndrome and myoglobinuric renal failure in a 50-year-old woman, which resolved after drug discontinuation and haemodialysis.
Population
A 50-year old woman
Design
Case_report
Authors
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Clinicians should monitor for this rare perphenazine reaction; single case leaves open population risk assessment.
Highlights a case of neuroleptic malignant syndrome with myoglobinuric renal failure induced by perphenazine, successfully treated with drug discontinuation and haemodialysis.
Nielsen et al. (1987) studied this question. Perphenazine treatment caused neuroleptic malignant syndrome and myoglobinuric renal failure in a 50-year-old woman, which resolved after drug discontinuation and haemodialysis.
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